Program · Biospecimen EDGE

The EDGE in biospecimens

End-to-end biospecimen procurement built by scientists who've run the full value chain, from collection through characterization to delivery. Longitudinal by design, functionally characterized, audit-ready, and the on-ramp to everything else Aqtual does.

01 · DESIGNTO YOUR PROTOCOL02 · SOURCEETHICALLY SOURCED03 · COLLECTLONGITUDINALLY04 · CHARACTERIZE → DELIVERFUNCTIONALLY CHARACTERIZEDCONDITIONRACOHORT SIZEn=120SAMPLE TYPEPlasma + PBMCCADENCEBaseline → Wk24IRB · CONSENTEDCHAIN OF CUSTODYBASELINEWK4WK12WK24ARM AARM BARM CDELIVERED · ANALYSIS-READY
n=120 DONORS · 4 TIMEPOINTS · FUNCTIONALLY CHARACTERIZED · OUTCOME-LINKED · ANALYSIS-READY
Longitudinal donorsDesigned to your protocol
01/The Aqtual difference

Sourced and characterized by the same team.

Most biospecimen programs hand you samples and stop. Aqtual runs the full value chain in-house: the scientists who source your cohort also characterize it on our active-chromatin platform. So samples don't just arrive collected; they arrive functionally characterized against the same ontology we use across every Aqtual program.

01DESIGN02SOURCE03COLLECT04CHARACTERIZE05DELIVER
02/Project Builder

Build a cohort, get a timeline, request a quote.

Tell us what you need; we'll show you a realistic timeline and route your request to our team the same business day.

Step 1 of 5

Indication

Therapeutic areaSingle choice
Specific disease stateAccrual ≈ 15 donors / month
Why we ask

Start with the disease, not the sample.

Every estimate is built from the accrual rate of real sites in that indication. Picking specific disease states sharpens the timeline and lets us match annotation to what your protocol actually needs.

  • 150+ disease states across 250+ partnered sites
  • Healthy and matched controls available in any area
Live estimateUpdating
43weeks to first delivery
Based on ≈ 15 donors / month in Rheumatology / Autoimmune
Protocol & site setup6w
Collection29w
Longitudinal window8w
QC & delivery4w
cfDNAac analysis3w
0w13w25w38w50w
Area
Rheumatology / Autoimmune
Indications
Rheumatoid arthritis
Samples
Plasma · double-spun K2-EDTA
Sourcing
Prospective collection
Donors
100
Cadence
Quarterly
Deliverable
Samples + cfDNAac
03/Delivery

What you get.

01

Novel signal access

Active-chromatin cfDNA measured directly, not inferred.
02

Longitudinal collection

The movement itself, sampled over time and outcome-linked.
03

Functional-state ontology

Samples delivered against a structured map you can compare across.
04/One collaboration, the whole platform

One cohort, many ways forward.

Because everything connects, a single EDGE engagement can extend across Aqtual's offering, with no re-sourcing, re-consenting, or re-collecting. The cohort you design here is the raw material the rest of the platform builds on.

Biospecimens
Raw material · feeds the stack
SequenceActive-chromatin cfDNA informs cellular biological function.
Tissue stateThe assay resolves a functional map of the involved tissues.
TrajectoryLongitudinal sampling informs on disease trajectory.
ApplicationsDetection, stratification, monitoring, and discovery, proven across rheumatoid arthritis, autoimmune disease, and oncology.
05/Get started

Start with the cohort.

Design a cohort and get a same-business-day response, then take it as far into the platform as your program needs.

Talk to our scientists