What It MeasuresActive-chromatin cfDNA others discard What It EnablesPrevention through drug development Supporting EvidenceThe published record behind the platform

Rheumatoid ArthritisA therapy selection test in clinical validation Platform in action

Every program here runs on the same active-chromatin cfDNA platform.

See how it works

Spotlight · RA testing

A blood-based test to inform treatment selection.

Most RA patients cycle through therapies before finding one that works. Aqtual's blood test reads synovial-associated active-chromatin signal to help match each patient to the right treatment class from the start.

Blood draw

70%+

Don't respond to first-line TNFi adequately

PRIMA-102

Clinical validation study

Explore the RA test

Platform DataTissue-level readouts from a single blood draw Functional Disease AtlasesDisease biology mapped onto blood signal Biospecimen ServicesAnnotated specimens procured end to end

MissionWhy we're building this Meet the TeamVeteran diagnostics leaders GalleryInside our Hayward facility

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